Prostate Cancer

The initiation of cancer is studied by focusing on the analysis of the Androgen pathway, which is to date the predominant factor in the regulation of prostate cancer. By highly developed imaging technology, the imaging of the 3D relation Read more

Prognostic and predictive biomarkers are pivotal for the management of clinical prostate cancer. Next to circulating markers in the blood, our research concentrates on the sensitivity and specificity of markers excreted in the urine, validated in our well annotated extensive banks of various biomaterials. Read more

Circulating and excreted extracellular vesicles derived from prostatic cells are of growing interest, as their contents include genomic and proteomic information representative for the intracellular metabolism. Quantification and contents are studied by patented techniques. Read more

The aim is the development of new computational algorithms, analysis methods, artificial intelligence and visualization tools that interrogate and integrate big genomic and clinical data sets for better understanding of cancer development. Read more

Based on the large library of in vitro, in vivo, and organoid models  our basic and translational research program is studying the resistance mechanisms to clinically applied drugs, and explores new possibilities for nuclear probe based imaging with high prostate specificity. Read more