ERASMUS UROLOGY RESEARCH

Prostate Cancer

The research on prostate cancer focuses among others on mechanisms that drive tumor growth, the development of tools to detect and grade prostate cancer in clinical samples and the development of novel therapeutic approaches for (resistant) prostate cancer. These aims are reflected in the following research lines:

Cancer initiation and progression

The initiation of cancer is studied by focusing on the analysis of the Androgen pathway, which is to date the predominant factor in the regulation of prostate cancer. By highly developed imaging technology, the imaging of the 3D relation Read more

Urinary biomarkers

Prognostic and predictive biomarkers are pivotal for the management of clinical prostate cancer. Next to circulating markers in the blood, our research concentrates on the sensitivity and specificity of markers excreted in the urine, validated in our well annotated extensive banks of various biomaterials. Read more

Extracellular vesicles

Circulating and excreted extracellular vesicles derived from prostatic cells are of growing interest, as their contents include genomic and proteomic information representative for the intracellular metabolism. Quantification and contents are studied by patented techniques. Read more

Cancer Computational Biology

The aim is the development of new computational algorithms, analysis methods, artificial intelligence and visualization tools that interrogate and integrate big genomic and clinical data sets for better understanding of cancer development. Read more

Xenograft and Organoid Models

Based on the large library of in vitro, in vivo, and organoid models  our basic and translational research program is studying the resistance mechanisms to clinically applied drugs, and explores new possibilities for nuclear probe based imaging with high prostate specificity. Read more

Epidemiology

The Urology Research Office, under the guidance of Prof. Monique Roobol, aims to transform clinical
and patient-reported outcome data into easy-to-use prediction tools that will help patients and their
caretakers in the many decisions they face during their patient’s journey.Read more

People

Guido Jenster

Guido Jenster

Professor

Wytske van Weerden

Wytske van Weerden

Associate Professor

Elena Martens

Elena Martens

Assistent Professor

Harmen van de Werken

Harmen van de Werken

Assistent Professor

Annelies van Hemelryk

PhD candidate

Ardalan Mansouri

Ardalan Mansouri

PhD candidate

Wilma Teubel

Wilma Teubel

Head Technician

Sigrun Erkens

Sigrun Erkens

Research Technician

Joke Veldhoven

Joke Veldhoven

Research Technician

Natasja Dits

Natasja Dits

Research Technician

Mirella Vredenbregt

Technician

Martin van Royen

Martin van Royen

Principle Investigator

Corrina de Ridder

Corrina de Ridder

Biotechnician

Debra Stuurman

Debra Stuurman

Biotechnician

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